Vulnerability of pediatric patients with mitochondrial disease to vaccine-preventable diseases

Vaccine-preventable diseases.

The panel addressed four main areas of vaccine development and use: diseases of public health importance for which no vaccine is available; diseases for which an existing licensed vaccine is not optimal and alternative vaccines are under development; diseases for which a vaccine exists but is not being used optimally; and diseases requiring vaccines of specialized or limited use, such as those ...

Immunisation and Vaccine Preventable Diseases

Evaluation of Antibody Response to Polysaccharide Vaccine and Switched Memory B Cells in Pediatric Patients with Inflammatory Bowel Disease

Background/Aims: Inflammatory bowel disease (IBD) is a chronic disease of the gastrointestinal tract, whose etiologies are still unknown. This study was performed to evaluate the humoral immune response in terms of B cell functions in selected IBD patients. Methods: Eighteen pediatric patients with IBD, including 12 cases of ulcerative colitis (UC) and six with Crohn disease (CD), were enrolled...

The vicar of vicarious vaccine-preventable diseases.

On this spring day, you have seen your fourth patient younger than age 24 months with a fever of 103.5°F for the past day or so, including your own granddaughter (Figure 1), who was being examined by your partner. Each child was without other symptoms except for being cranky, anorexic, non-toxic appearing, and totally unappreciative of any physician examination. In the “old days,” many of these...

Issues in pediatric vaccine-preventable diseases in low- to middle-income countries

The highest burden of pediatric vaccine-preventable disease is found in developing nations where resource constraints pose the greatest challenge, impacting disease diagnosis and surveillance as well as the implementation of large scale vaccination programmes. In November 2012, a Working Group Meeting convened in Casablanca to describe and discuss the status with respect to 8 vaccine-preventabl...